Stem Cell Biology and Regenerative Medicine In Ophthalmology : ebook

Stem Cell Biology and Regenerative Medicine  In Ophthalmology

1 The Eye as a Target Organ for Stem Cell Therapy . . . . . . . . . . . . . 1

Mark A. Fields, John Hwang, Jie Gong, Hui Cai,

and Lucian V. Del Priore

2 Stem Cells in Oculofacial Plastic Surgery . . . . . . . . . . . . . . . . . . . . 31

Bryan J. Winn and Mary Whitman

3 The Current Status of Corneal Limbal Stem Cell

Transplantation in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43

Roy S. Chuck, Alexandra A. Herzlich, and Philip Niles

4 Lens Differentiation from Embryonic Stem (ES) and Induced

Pluripotent Stem (iPS) Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57

Ales Cvekl, Ying Yang, Yang Jing, and Qing Xie

5 Stem Cells and Glaucoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75

Jonathan Hertz and Jeffrey L. Goldberg

6 Bone Marrow Stem Cells in Retinal Disease . . . . . . . . . . . . . . . . . . 99

Louis K. Chang

7 Stem Cells, Mechanism-Based Therapies and Regenerative

Medicine Approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107

Xining He, Deniz Erol, and Stephen H. Tsang

8 New Developments in Retinal Cell Transplantation and the

Impact of Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121

Peter Gouras

9 Cancer Stem Cells in Uveal Melanoma . . . . . . . . . . . . . . . . . . . . . . 139

Helen Kalirai, Bertil E. Damato, and Sarah E. Coupland

10 Current Ex-Vivo Gene Therapy Technologies and Future

Developments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153

Chen-Hsien Su and Deniz Erol

ix

11 Stem Cell-Based Therapeutics in Ophthalmology: Application

Toward the Design of Clinical Trials . . . . . . . . . . . . . . . . . . . . . . . 171

Rony Gelman and Stephen H. Tsang

About the Editor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181

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